China Presents Revolutionary Hydrogel Patch: 90% Healing of Diabetic Ulcers in Just 12 Days

Breakthrough in Diabetic Wound Treatment: Hope for Patients in Bulgaria and the World

Diabetes is among the leading health challenges in Bulgaria and worldwide. Chronic wounds – especially diabetic ulcers – are difficult to treat, but a new development from China fundamentally changes the approach to this problem.

How Does the New 'Smart' Patch Work?

• Combination of biocompatible GelMA-based gel and special microvesicles with microRNA miR-221-3p – an active ingredient that stimulates healing.
• The patch blocks a protein (TSP-1) that stops the formation of new blood vessels in diabetes.
• Activates angiogenesis – the process of forming new healthy tissue and blood vessels.
• The moist environment and controlled release of therapeutic microvesicles ensure rapid and quality regeneration.

In experiments on diabetic mice, the patch leads to 90% wound closure in 12 days – many times faster than classic therapies.
Increased vascularization and cell restoration are key factors – the patch not only accelerates healing but supports the formation of stable tissue.

Possible Medical Applications

• The technology has potential not only for diabetic wounds but also for other chronic skin lesions, vascular ulcers, bone and cartilage restoration.
• The miRNA and GelMA-based engineering platform can be adapted for other types of wounds and therapies.

Rapid development and transfer of the technology to the European and Bulgarian market is expected – an area where the healthcare sector and innovations in our country have long traditions.

Significance for Bulgaria

Such a breakthrough could reduce the risk of infections and amputations, improve quality of life with diabetes, and motivate Bulgarian scientists and hospitals to implement new biomedical approaches.
With the introduction of innovative therapies, patients in our country will receive less invasive and more effective solutions for chronic wounds – a topic of enormous social importance.

Conclusion

The revolutionary 'smart' hydrogel patch from China sets a new standard for regenerative medicine. For patients, doctors, and the scientific community in Bulgaria, this is not just news, but a future – with more hope, fewer complications, and new possibilities for treating diabetic and other chronic wounds.