A road accident at the Sokolovo junction has partly closed the road between Karnobat and Aytos, the Road Infrastructure Agency said.
Drivers can take a detour along the Trakia motorway.
It is the second crash near Karnobat in a few days. Earlier in October, two people were injured at a junction where the road from Karnobat to Shumen crosses the road from Lozarevo to Karnobat.
The agency said there were no reports so far of injuries or property damage.